research & publications

HIV RESEARCH

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  • 7 results found
  • Effects of a mobile phone short message service on antiretroviral treatment adherence in Kenya (WelTel Kenya1): a randomised trial

    Mobile (cell) phone communication has been suggested as a method to improve delivery of health services. However, data on the effects of mobile health technology on patient outcomes in resource-limited settings are limited. We aimed to assess whether mobile phone communication between health-care workers and patients starting antiretroviral therapy in Kenya improved drug adherence and suppression of plasma HIV-1 RNA load.

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  • A Simplified tool for measuring adherence to highly active antiretroviral therapy (HAART) in resource limited setting. The experience of Maragua District Hospital, Kenya

    Viral load is a good predictor of treatment failure for patients on HAART. However, in
    resource limited setting, viral load tests are not widely available. High adherence rates have been associated with
    good treatment outcomes. Information on the use ofsimplified tools to measure adherence in the public sector
    is scarce. We intend to demonstrate that a simple tool can be used routinely to monitor adherence in patients
    on HAART.

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  • Innovative approaches to scale up HIV counseling and testing among urban youth in Kenya P. Wambua1, M. Hassan2

    Gjue ( know yourself) is a strategy developed by a consortium of youth organizations led by I Choose
    Life- Africa, Liverpool treatment and services and National Organization of Peer Educators to provide HIV testing to over
    1 million youth in Kenya. Going by the slogan, Gjue Niko sure Najijua ( I am sure I know my HIV status) , its
    main attractiveness is the use of glow- in- the- dark wristbands for everyone who goes for testing under the campaign.
    Each glow in dark wristband has a serial number to identify each wristband and to keep track of how many people have
    been tested. It also has a toll free number inscribed on it which the youth can call to get information regarding
    reproductive health and other post test services.

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  • Evaluating Demand Creation Strategies for Voluntary Medical Male Circumcision (VMMC) in Kenya (TASCO)

    The purpose of this study is to evaluate the impact of two interventions - Inter-Personal
    Communication [IPC] and Dedicated Service Outlets [DSOs] - in recruiting men aged 25-39 years for
    Voluntary Medical Male Circumcision (VMMC) services.

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  • Simplifying the Shang Ring Technique for Circumcision of Men and Boys

    The study, to be conducted in two phases, will examine procedural and clinical outcomes, as well as
    participant and provider acceptability, of adaptations of the Shang Ring technique for male
    circumcision that would simplify its use and increase its acceptability.
     Phase I will be non-comparative for exploration of the no-flip technique for Shang Ring circumcision
    (i.e. all participants will be circumcised using the no-flip Shang Ring technique). Historical data from
    standard Shang Ring circumcisions conducted in Africa (Kenya, Uganda and Zambia) will be used
    as the comparison group. Men will be randomized to removal at 7 days after circumcision vs.
    delayed removal, to assess occurrence and safety of spontaneous detachments following
    circumcision with the no-flip technique.
     Phase 2 will compare the use of topical vs. injectable anesthesia for Shang Ring circumcision.
    Participants will be randomized to topical vs. injectable anesthesia in a 2:1 ratio. The investigators
    rationalize the 2:1 randomization scheme given that the investigators will have just completed Phase
    I in which 200 men and boys will have been circumcised using the no-flip technique with injected
    anesthesia. However, given the subjectivity associated with using reported pain as the primary
    endpoint, the investigators believe it is critical to randomize participants in this phase of the study.
    Eligibility

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  • Mobile Phone Technology for Prevention of Mother-to-Child Transmission of HIV: Acceptability, Effectiveness, and Cost

    Although gains have been made in achieving the health-related Millennium Development Goals
    (MDG), much is still needed in countries affected by high levels of HIV/AIDS. Prevention of motherto-child transmission (PMTCT) is a cornerstone strategy in reducing infant mortality from HIV. The
    study will employ a cluster randomized control trial (cRCT) with 26 health facilities randomized to two
    arms (intervention or control) to determine the effect of mobile phone technology on completion of
    key PMTCT milestones from antenatal to six weeks postpartum. The study will examine the
    acceptability, effectiveness, and cost of implementing a PMTCT-focused mHealth strategy among
    HIV-infected pregnant women, health workers, and male partners.

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  • Kick Out HIV Stigma

    1 Million young people tested for HIV by December 1st 2016
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